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SET Antibody - N-terminal region : HRP (ARP56542_P050-HRP)

Product Specifications

Gene Name

SET nuclear oncogene

Gene Aliases

2PP2A, IGAAD, MRD58, TAF-I, I2PP2A, IPP2A2, PHAPII, TAF-IBETA

Gene ID

6418

Swiss Prot

B2RCX0

Accession Number

NP_003002

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SET

Target

SET is a multitasking protein, involved in apoptosis, transcription, nucleosome assembly and histone binding. Isoform 2 anti-apoptotic activity is mediated by inhibition of the GZMA-activated DNase, NME1. In the course of cytotoxic T-lymphocyte (CTL) -indu

Partner Proteins

SDCBP; FAM111B; THAP7; MEOX2; HUWE1; UBC; APP; Fbxl16; FTSJ3; GART; XRCC6; FTH1; SWAP70; FAF1; HSPH1; PAICS; FARSB; RANBP3; HIRIP3; UGP2; TARS; SUPT5H; PLOD2; PARK2; FOS; MTERF1; PRKAR1A; MDM2; UBD; SOX2; ICAM1; GZMK; CD81; IGSF8; NUPR1; NUCB1; JUNB; FN1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, IP, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

32kDa

References & Citations

Liu, Z., (2008) Mol. Cell 29 (6), 665-678

Shipping Conditions

Wet Ice

Protein Length

277

NCBI Gene Symbol

SET

NCBI GB Accession Number

SET

Host or Source

Rabbit

Protein Name

CDNA, FLJ96345, Homo sapiens SET translocation (myeloid leukemia-associated) (SET), mRNA EMBL BAG37717.1

Nucleotide Accession Number

NM_003011

Peptide Sequence

IDEVQNEIDRLNEQASEEILKVEQKYNKLRQPFFQKRSELIAKIPNFWVT

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