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RPA1 Antibody - middle region : Biotin (ARP56526_P050-Biotin)

Product Specifications

Gene Name

Replication protein A1, 70kDa

Gene Aliases

HSSB, RF-A, RP-A, REPA1, RPA70, MST075

Gene ID

6117

Swiss Prot

P27694

Accession Number

NP_002936

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human RPA1

Target

RPA1 plays an essential role in several cellular processes in DNA metabolism including replication, recombination and DNA repair. RPA1 binds and subsequently stabilizes single-stranded DNA intermediates and thus prevents complementary DNA from reannealing

Partner Proteins

STRA13; UBC; MTUS2; APITD1; PCNA; SUMO2; FBXO18; ATRX; MAP4; CAPRIN1; LMO7; LIG3; LDHA; ITGB1; IMPDH2; ILF3; ILF2; HSPB1; HSPA8; HSPA5; HNRNPU; HNRNPL; HNRNPK; HNRNPH1; HNRNPF; HNRNPD; HNRNPAB; HNRNPA2B1; HNRNPA1; HCFC1; GTF3C2; GTF2I; GTF2H3; GAPDH; XRCC

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

RPA1 is strongly supported by BioGPS gene expression data to be expressed in 721_B, HeLa RPA1 is supported by BioGPS gene expression data to be expressed in MCF7

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Sheep: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

68kDa

References & Citations

Tomida, J., (2008) J. Biol. Chem. 283 (14), 9071-9079

Shipping Conditions

Wet Ice

Protein Length

616

NCBI Gene Symbol

RPA1

NCBI GB Accession Number

RPA1

Host or Source

Rabbit

Protein Name

Replication protein A 70 kDa DNA-binding subunit

Nucleotide Accession Number

NM_002945

Peptide Sequence

TLWGEDADKFDGSRQPVLAIKGARVSDFGGRSLSVLSSSTIIANPDIPEA

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