RFC1 Antibody - middle region : Biotin (ARP56522_P050-Biotin)

Product Specifications

Gene Name

Replication factor C (activator 1) 1, 145kDa

Gene Aliases

A1, RFC, PO-GA, RECC1, CANVAS, MHCBFB, RFC140

Gene ID

5981

Swiss Prot

P35251-2

Accession Number

NP_002904

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human RFC1

Target

The protein encoded by this gene is the large subunit of replication factor C, which is a five subunit DNA polymerase accessory protein. Replication factor C is a DNA-dependent ATPase that is required for eukaryotic DNA replication and repair. The protein acts as an activator of DNA polymerases, binds to the 3' end of primers, and promotes coordinated synthesis of both strands. It also may have a role in telomere stability.

Partner Proteins

SPRTN; UBC; PCNA; RPA3; RPA2; RPA1; YWHAQ; SMC1A; RFC4; NOTCH1; WDR18; RBM14; RFC5; RFC3; RFC2; LAMP2; MYOC; SIRT7; SUMO2; HDGF; RAD17; CSNK2B; tat; SAP25; ZSCAN1; SSBP3; PMS1; CEBPA; BRCA1; RFC1; BRD4; HDAC1; CASP3; TCEAL1; CCND1; RELA; CDK4; CHTF18; SMA

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.