RASGRF1 Antibody - N-terminal region : Biotin (ARP56516_P050-Biotin)

Product Specifications

Gene Name

Ras protein-specific guanine nucleotide-releasing factor 1

Gene Aliases

GNRP, GRF1, CDC25, GRF55, CDC25L, H-GRF55, PP13187, ras-GRF1

Gene ID

5923

Swiss Prot

Q13972-2

Accession Number

NP_722522

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human RASGRF1

Target

The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein.

Partner Proteins

EHD4; SNRNP70; CEBPA; ADRBK1; MYC; UBC; TNK2; YWHAE; USP8; RAC1; PRKACA; NTRK2; RRAS2; NTRK3; NTRK1; RHOA; YWHAB; PPP1R9B; MARK3; HRAS

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 85%; Rabbit: 93%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

54kDa

References & Citations

Iguchi, T., (2007) Int. J. Oncol. 31 (2), 285-291

Shipping Conditions

Wet Ice

Specificity

Predicted to recognized both human RASGRF1 isoforms (145, 55kD)

Protein Length

489

NCBI Gene Symbol

RASGRF1

NCBI GB Accession Number

RASGRF1

Host or Source

Rabbit

Protein Name

Ras-specific guanine nucleotide-releasing factor 1

Nucleotide Accession Number

NM_153815

Peptide Sequence

RELDNNRSALSAASAFAIATAGANEGTPNKEKYRRMSLASAGFPPDQRNG

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