RANGAP1 Antibody - N-terminal region : Biotin (ARP56509_P050-Biotin)
Product Specifications
Gene Name
Ran GTPase activating protein 1
Gene Aliases
SD, Fug1, RANGAP
Gene ID
5905
Swiss Prot
P46060
Accession Number
NP_002874
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human RANGAP1
Target
RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1,000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGA
Partner Proteins
SENP2; SENP1; SUMO1; UBE2I; SUMO2; SUMO3; RANBP2; UBC; NEDD8; RNF2; rev; TP53RK; EFTUD1; NIF3L1; RPRD1B; OSGEP; PANK4; THG1L; NSUN2; UFM1; IPO11; SH3GLB1; TPRKB; EEF2K; DBNL; KIAA1279; ACTR2; ACTR3; ARPC1B; SAE1; TPD52L2; PPP2R5D; LPP; CALU; BAG1; ARPC2
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
63kDa
References & Citations
Ewing, R.M., Mol. Syst. Biol. 3, 89 (2007)
Shipping Conditions
Wet Ice
Protein Length
587
NCBI Gene Symbol
RANGAP1
NCBI GB Accession Number
RANGAP1
Host or Source
Rabbit
Protein Name
Ran GTPase-activating protein 1
Nucleotide Accession Number
NM_002883
Peptide Sequence
MASEDIAKLAETLAKTQVAGGQLSFKGKSLKLNTAEDAKDVIKEIEDFDS
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