PSMD3 Antibody - middle region: Biotin (ARP56480_P050-Biotin)
Product Specifications
Gene Name
Proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
Gene Aliases
S3, P58, RPN3, TSTA2
Gene ID
5709
Swiss Prot
O43242
Accession Number
NP_002800
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human PSMD3
Target
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid.
Partner Proteins
CEP44; ZBTB43; HUWE1; SHFM1; SPRTN; SNAI2; STAU1; PSMD14; UBC; UBQLN1; FLNC; FLNB; PSMD8; PSMD4; PSMD1; PSMC6; PSMC5; PSMC4; PSMC3; PSMC2; PSMC1; KCMF1; UCHL5; KIAA0368; ADRM1; TXNL1; SQSTM1; RPS28; RPS21; RPS15A; RPS13; RPS8; PSMD12; PSMD11; PARK2; FBXO6
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 82%; Zebrafish: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
61kDa
Shipping Conditions
Wet Ice
Protein Length
534
NCBI Gene Symbol
PSMD3
Protein Name
26S proteasome non-ATPase regulatory subunit 3
Nucleotide Accession Number
NM_002809
Curated Selection
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