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POLB Antibody - middle region : Biotin (ARP56406_P050-Biotin)

Product Specifications

Gene Name

Polymerase (DNA directed), beta

Gene Aliases

MGC125976

Gene ID

5423

Swiss Prot

P06746

Accession Number

NP_002681

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human POLB

Target

In eukaryotic cells, DNA polymerase beta (POLB) performs base excision repair (BER) required for DNA maintenance, replication, recombination, and drug resistance. Also see POLA (MIM 312040) .

Partner Proteins

TPP2; SRPK2; XRCC1; RAD27; HHV8GK18_gp81; UBC; UNG; STUB1; HUWE1; PARP1; PCNA; NCAPG; WRN; TAF1D; KAT7; RAD1; TLE1; PRKCA; APEX1; PNKP; NEIL1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

38kDa

References & Citations

Batra, V.K., (2008) Mol. Cell 30 (3), 315-324

Shipping Conditions

Wet Ice

Protein Length

335

NCBI Gene Symbol

POLB

NCBI GB Accession Number

POLB

Host or Source

Rabbit

Protein Name

DNA polymerase beta

Nucleotide Accession Number

NM_002690

Peptide Sequence

GPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEML

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