PIM1 Antibody - N-terminal region: Biotin (ARP56390_P050-Biotin)
Product Specifications
Gene Name
Pim-1 oncogene
Gene Aliases
PIM
Gene ID
5292
Swiss Prot
P11309-2
Accession Number
NP_002639
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human PIM1
Target
PIM1 may affect the structure or silencing of chromatin by phosphorylating HP1 gamma/CBX3. Isoform 2 promotes the G1/S transition of the cell cycle via up-regulation of CDK2 activity and phosphorylation of CDKN1B, resulting in enhanced nuclear export and
Partner Proteins
FXR2; NHLH1; FH; BEND7; HEXIM2; BANP; TFPT; ZBTB1; UBC; APP; MARK3; HSP90AA1; HSPA4; PIM1; MDM2; ELAVL1; FZR1; SKP2; PPP2R5E; PPP2R4; PPP2CA; PIN1; CDC34; CDC20; ABCB1; HIST2H3C; MYC; MAX; SNX6; CBX1; CBX3; BAD; HIST3H3; SND1; PTPRO; NFATC1; SHMT1; EPHA3
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
PIM1 is supported by BioGPS gene expression data to be expressed in HEK293T
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
45kDa
Shipping Conditions
Wet Ice
Protein Length
404
NCBI Gene Symbol
PIM1
Protein Name
Serine/threonine-protein kinase pim-1
Nucleotide Accession Number
NM_002648
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