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MTRF1L Antibody - N-terminal region : Biotin (ARP56319_P050-Biotin)

Product Specifications

Gene Name

Mitochondrial translational release factor 1 like

Gene Aliases

MRF1L, HMRF1L, mtRF1a

Gene ID

54516

Swiss Prot

Q9UGC7

Accession Number

NP_001107656

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human RF1ML

Target

The protein encoded by this gene plays a role in mitochondrial translation termination, and is thought to be a release factor that is involved in the dissociation of the complete protein from the final tRNA, the ribosome, and the cognate mRNA. This protein acts upon UAA and UAG stop codons, but has no in vitro activity against UGA, which encodes tryptophan in human mitochondrion, or, the mitochondrial non-cognate stop codons, AGA and AGG. This protein shares sequence similarity to bacterial release factors. Pseudogenes of this gene are found on chromosomes 4, 8, and 11. Alternative splicing results in multiple transcript variants.

Partner Proteins

UBC

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity purified

Concentration

0.5 mg/ml

Homology

Cow: 86%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 77%; Rabbit: 92%; Rat: 83%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

29 kDa

References & Citations

Nozaki, Y., (2008) Genes Cells 13 (5), 429-438

Shipping Conditions

Wet Ice

Protein Length

271

NCBI Gene Symbol

MTRF1L

NCBI GB Accession Number

MTRF1L

Host or Source

Rabbit

Protein Name

Peptide chain release factor 1-like, mitochondrial

Nucleotide Accession Number

NM_001114184.2

Peptide Sequence

MRSRVLWGAARWLWPRRAVGPARRPLSSGSPPLEELFTRGGPLRTFLERQ

Frequently Asked Questions

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