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MTMR12 Antibody - middle region : Biotin (ARP56274_P050-Biotin)

Product Specifications

Gene Name

Myotubularin related protein 12

Gene Aliases

3-PAP, PIP3AP

Gene ID

54545

Swiss Prot

Q9C0I1

Accession Number

NP_001035536

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human MTMR12

Target

MTMR12 inactives phosphatase that plays a role as an adapter for the phosphatase myotubularin to regulate myotubularin intracellular location.Phosphatidylinositide 3-kinase-derived membrane-anchored phosphatidylinositides, such as phosphatidylinositol 3-phosphate (PtdIns (3) P), regulate diverse cellular processes. The protein encoded by this gene functions as an adaptor subunit in a complex with an active PtdIns (3) P 3-phosphatase. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined.

Partner Proteins

YWHAB; UBC; MTM1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

86kDa

References & Citations

Nandurkar, H.H., (2003) Proc. Natl. Acad. Sci. U.S.A. 100 (15), 8660-8665

Shipping Conditions

Wet Ice

Protein Length

747

NCBI Gene Symbol

MTMR12

NCBI GB Accession Number

MTMR12

Host or Source

Rabbit

Protein Name

Myotubularin-related protein 12

Nucleotide Accession Number

NM_001040446

Peptide Sequence

RNSARLSSLFPFALLQRHSSKPVLPTSGWKALGDEDDLAKREDEFVDLGD

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