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EXOC4 Antibody - N-terminal region : HRP (ARP56253_P050-HRP)

Selected Variant

ARP56253_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Exocyst complex component 4

Gene Aliases

SEC8, Sec8p, SEC8L1

Gene ID

60412

Swiss Prot

Q8TAR2

Accession Number

NP_001032203

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human EXOC4

Target

The specific function of this protein remains unknown.The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Partner Proteins

SUMO2; UBC; EXOC2; EXOC7; ATG5; ATG12; BECN1; EXOC8; EGFR; EXOC1; EXOC3; nef; IQCB1; EXOC5; UBD; MYO5A; DTNBP1; CEP63; DISC1; Poc1b; GTF2E2; DLGAP4; DLG3; RALA; GRIN2B; DLG4; MYC

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

54kDa

References & Citations

Pohl, C. (2008) Cell 132 (5), 832-845

Shipping Conditions

Wet Ice

Protein Length

473

NCBI Gene Symbol

EXOC4

NCBI GB Accession Number

EXOC4

Host or Source

Rabbit

Protein Name

EXOC4 protein EMBL AAH26174.1

Nucleotide Accession Number

NM_001037126

Peptide Sequence

MAAEAAGGKYRSTVSKSKDPSGLLISVIRTLSTSDDVEDRENEKGRLEEA

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