EXOC4 Antibody - N-terminal region : Biotin (ARP56253_P050-Biotin)
Product Specifications
Gene Name
Exocyst complex component 4
Gene Aliases
SEC8, Sec8p, SEC8L1
Gene ID
60412
Swiss Prot
Q8TAR2
Accession Number
NP_001032203
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human EXOC4
Target
The specific function of this protein remains unknown.The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Partner Proteins
SUMO2; UBC; EXOC2; EXOC7; ATG5; ATG12; BECN1; EXOC8; EGFR; EXOC1; EXOC3; nef; IQCB1; EXOC5; UBD; MYO5A; DTNBP1; CEP63; DISC1; Poc1b; GTF2E2; DLGAP4; DLG3; RALA; GRIN2B; DLG4; MYC
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
54kDa
References & Citations
Pohl, C. (2008) Cell 132 (5), 832-845
Shipping Conditions
Wet Ice
Protein Length
473
NCBI Gene Symbol
EXOC4
NCBI GB Accession Number
EXOC4
Host or Source
Rabbit
Protein Name
EXOC4 protein EMBL AAH26174.1
Nucleotide Accession Number
NM_001037126
Peptide Sequence
MAAEAAGGKYRSTVSKSKDPSGLLISVIRTLSTSDDVEDRENEKGRLEEA
Frequently Asked Questions
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