GOPC Antibody - middle region : Biotin (ARP56215_P050-Biotin)

Product Specifications

Gene Name

Golgi-associated PDZ and coiled-coil motif containing

Gene Aliases

CAL, FIG, PIST, GOPC1, dJ94G16.2

Gene ID

57120

Swiss Prot

Q9HD26

Accession Number

NP_001017408

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human GOPC

Target

GOPC plays a role in intracellular protein trafficking and degradation. GOPC may regulate CFTR chloride currents and acid-induced ACCN3 currents by modulating cell surface expression of both channels. GOPC may also regulate the intracellular trafficking of the ADR1B receptor. GOPC may play a role in autophagy. Overexpression of GOPC results in CFTR intracellular retention and degradation in the lysosomes.PIST is a PDZ domain-containing Golgi protein. PDZ domains contain approximately 90 amino acids and bind the extreme C terminus of proteins in a sequence-specific manner.[supplied by OMIM].

Partner Proteins

BATF; SSNA1; VTN; MYLK; HCK; FOSL2; DPYD; RPL13AP17; C17orf67; ZSCAN1; LCLAT1; FAM9B; ZBTB49; ZNF564; SPATA8; RNF183; MORN4; MYOCD; MUM1; ZNF587; SLC25A18; CCDC102B; AKIRIN1; MRPL1; SEMA4G; RNF220; FAM90A1; PID1; ZNF581; CERCAM; RHOQ; PARK7; STARD3; HSF1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.