GOPC Antibody - N-terminal region : Biotin (ARP56214_P050-Biotin)
Product Specifications
Gene Name
Golgi-associated PDZ and coiled-coil motif containing
Gene Aliases
CAL, FIG, PIST, GOPC1, dJ94G16.2
Gene ID
57120
Swiss Prot
Q9HD26
Accession Number
NP_001017408
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human GOPC
Target
GOPC plays a role in intracellular protein trafficking and degradation. GOPC may regulate CFTR chloride currents and acid-induced ACCN3 currents by modulating cell surface expression of both channels. GOPC may also regulate the intracellular trafficking of the ADR1B receptor. GOPC may play a role in autophagy. Overexpression of GOPC results in CFTR intracellular retention and degradation in the lysosomes.PIST is a PDZ domain-containing Golgi protein. PDZ domains contain approximately 90 amino acids and bind the extreme C terminus of proteins in a sequence-specific manner.[supplied by OMIM].
Partner Proteins
BATF; SSNA1; VTN; MYLK; HCK; FOSL2; DPYD; RPL13AP17; C17orf67; ZSCAN1; LCLAT1; FAM9B; ZBTB49; ZNF564; SPATA8; RNF183; MORN4; MYOCD; MUM1; ZNF587; SLC25A18; CCDC102B; AKIRIN1; MRPL1; SEMA4G; RNF220; FAM90A1; PID1; ZNF581; CERCAM; RHOQ; PARK7; STARD3; HSF1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 86%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
50kDa
References & Citations
Wolde, M., (2007) J. Biol. Chem. 282 (11), 8099-8109
Shipping Conditions
Wet Ice
Protein Length
454
NCBI Gene Symbol
GOPC
NCBI GB Accession Number
GOPC
Host or Source
Rabbit
Protein Name
Golgi-associated PDZ and coiled-coil motif-containing protein
Nucleotide Accession Number
NM_001017408
Peptide Sequence
EVLEKEFDKAFVDVDLLLGEIDPDQADITYEGRQKMTSLSSCFAQLCHKA
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