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Ppp2r2d Antibody - C-terminal region : HRP (ARP56157_P050-HRP)

Product Specifications

Gene Name

Protein phosphatase 2, regulatory subunit B, delta isoform

Gene Aliases

MDS02, MDS026, D7Ertd753, D7Ertd753e, 1300017E19Rik

Gene ID

52432

Swiss Prot

Q925E7

Accession Number

NP_080667

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide corresponding to a region of Mouse

Target

Ppp2r2d is a B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. The activity of PP2A complexes containing PPP2R2D (PR55-delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis. During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors. Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment.

Partner Proteins

Supt5; SMURF1; SMAD3; SMAD2

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%; Zebrafish: 93%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

50kDa

Shipping Conditions

Wet Ice

Protein Length

453

NCBI Gene Symbol

PPP2R2D

NCBI GB Accession Number

Ppp2r2d

Host or Source

Rabbit

Protein Name

Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform

Nucleotide Accession Number

NM_026391

Peptide Sequence

RRDVTLEASRENSKPRASLKPRKVCTGGKRKKDEISVDSLDFNKKILHTA

Subunit

B delta isoform

Frequently Asked Questions

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