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PCCB Antibody - middle region : Biotin (ARP56116_P050-Biotin)

Product Specifications

Gene Name

Propionyl CoA carboxylase, beta polypeptide

Gene Aliases

DKFZp451E113

Gene ID

5096

Swiss Prot

P05166

Accession Number

NP_000523

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PCCB

Target

PCCB is a subunit of the propionyl-CoA carboxylase (PCC) enzyme, which is involved in the catabolism of propionyl-CoA. PCC is a mitochondrial enzyme that probably acts as a dodecamer of six alpha subunits and six beta subunits. Defects in this gene are a cause of propionic acidemia type II (PA-2) .

Partner Proteins

HUWE1; PARK2; IFIT1; INPPL1; EPS15; UBE2N; UBC; EBNA-LP; ICT1; PCCB; PCCA

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

58kDa

References & Citations

Desviat, L.R., (2006) J. Hum. Genet. 51 (11), 992-997

Shipping Conditions

Wet Ice

Protein Length

539

NCBI Gene Symbol

PCCB

NCBI GB Accession Number

PCCB

Host or Source

Rabbit

Protein Name

Propionyl-CoA carboxylase beta chain, mitochondrial

Nucleotide Accession Number

NM_000532

Peptide Sequence

PGFLPGTAQEYGGIIRHGAKLLYAFAEATVPKVTVITRKAYGGAYDVMSS

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