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PTS Antibody - N-terminal region : FITC (ARP56099_P050-FITC)

Selected Variant

ARP56099_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

6-pyruvoyltetrahydropterin synthase

Gene Aliases

PTPS

Gene ID

5805

Swiss Prot

Q03393

Accession Number

NP_000308

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human PTPS

Target

The enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH (4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia.

Partner Proteins

COIL; SDCBP; LNX1; THAP10; PTS; ASB5; ASB1; WDYHV1; FXR2; UBC; SMURF1; AGO4; FNDC5; PRKG2; PBRM1; PRKDC; ATR; ATM

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

15kDa

Shipping Conditions

Wet Ice

Protein Length

145

NCBI Gene Symbol

PTS

NCBI GB Accession Number

PTS

Host or Source

Rabbit

Protein Name

6-pyruvoyl tetrahydrobiopterin synthase

Peptide Sequence

SKFLSDEENLKLFGKCNNPNGHGHNYKVVVTVHGEIDPATGMVMNLADLK

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