ERVFRD-1 Antibody - C-terminal region : FITC (ARP56009_P050-FITC)
Selected Variant
ARP56009_P050-FITC
Size: 100 µL
Product Specifications
Gene Name
Endogenous retrovirus group FRD, member 1
Gene Aliases
EnvFRD, UNQ6191, ERVFRDE1, GLLL6191, HERV-FRD, HERV-W/FRD
Gene ID
405754
Swiss Prot
P60508
Accession Number
NP_997465
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human ERVFRD-1
Target
Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of a human endogenous retrovirus provirus on chromosome 6 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product plays a major role in placental development and trophoblast fusion. The protein has the characteristics of a typical retroviral envelope protein, including a cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer.
Partner Proteins
APP
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
59kDa
Shipping Conditions
Wet Ice
Protein Length
538
NCBI Gene Symbol
ERVFRD-1
NCBI GB Accession Number
ERVFRD-1
Host or Source
Rabbit
Protein Name
HERV-FRD_6p24.1 provirus ancestral Env polyprotein
Peptide Sequence
PLVSLLLLLLFGPCLLNLITQFVSSRLQAIKLQTNLSAGRHPRNIQESPF
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