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HIPK1 Antibody - middle region : Biotin (ARP55866_P050-Biotin)

Product Specifications

Gene Name

Homeodomain interacting protein kinase 1

Gene Aliases

Myak, Nbak2

Gene ID

204851

Swiss Prot

Q86Z02

Accession Number

NP_938009

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human HIPK1

Target

HIPK1 may play a role as a corepressor for homeodomain transcription factors. HIPK1 phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. HIPK1 may be involved in malignant squamous cell tumor formation.The protein encoded by this gene belongs to the Ser/Thr family of protein kinases and HIPK subfamily. It phosphorylates homeodomain transcription factors and may also function as a co-repressor for homeodomain transcription factors. Alternative splicing results in four transcript variants encoding four distinct isoforms.

Partner Proteins

FHL3; HIPK1; DDX54; HAX1; NEB; A2M; PRPF40A; UBC; SKIL; PARK7; ATP13A2; RASSF5; SIAH1; UBE2I; GLUL; SNIP1; DAXX; NKX2-5; TP53; RUNX1; HOXD4

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 86%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

131kDa

References & Citations

Li, X., (2005) J. Biol. Chem. 280 (15), 15061-15070

Shipping Conditions

Wet Ice

Protein Length

1210

NCBI Gene Symbol

HIPK1

NCBI GB Accession Number

HIPK1

Host or Source

Rabbit

Protein Name

Homeodomain-interacting protein kinase 1

Nucleotide Accession Number

NM_198268

Peptide Sequence

PLNLSQNQQSSAAPTSQERSSNPAPRRQQAFVAPLSQAPYTFQHGSPLHS

Frequently Asked Questions

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