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SPDYA Antibody - middle region : HRP (ARP55846_P050-HRP)

Product Specifications

Gene Name

Speedy homolog A (Xenopus laevis)

Gene Aliases

SPY1, SPDY1, RINGO3, RINGOA

Gene ID

245711

Swiss Prot

Q5MJ70

Accession Number

NP_877433

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SPDYA

Target

SPDYA regulates the G1/S phase transition of the cell cycle by binding and activating CDC2, CDK2 and CDKN1B/KIP1. SPDYA can activate CDK2 without promoting CDK2 phosphorylation. SPDYA mediates cell survival during the DNA damage process through activation of CDK2.

Partner Proteins

CDK2; UBC; SKP2; CDKN1B

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

36kDa

References & Citations

McAndrew, C.W., (2007) Cell Cycle 6 (15), 1937-1945

Shipping Conditions

Wet Ice

Protein Length

313

NCBI Gene Symbol

SPDYA

NCBI GB Accession Number

SPDYA

Host or Source

Rabbit

Protein Name

Speedy protein A

Nucleotide Accession Number

NM_182756

Peptide Sequence

HTAGVTEKHSQDSYNSLSMDIIGDPSQAYTGSEVVNDHQSNKGKKTNFLK

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