SPDYA Antibody - middle region : Biotin (ARP55846_P050-Biotin)
Product Specifications
Gene Name
Speedy homolog A (Xenopus laevis)
Gene Aliases
SPY1, SPDY1, RINGO3, RINGOA
Gene ID
245711
Swiss Prot
Q5MJ70
Accession Number
NP_877433
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human SPDYA
Target
SPDYA regulates the G1/S phase transition of the cell cycle by binding and activating CDC2, CDK2 and CDKN1B/KIP1. SPDYA can activate CDK2 without promoting CDK2 phosphorylation. SPDYA mediates cell survival during the DNA damage process through activation of CDK2.
Partner Proteins
CDK2; UBC; SKP2; CDKN1B
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
36kDa
References & Citations
McAndrew, C.W., (2007) Cell Cycle 6 (15), 1937-1945
Shipping Conditions
Wet Ice
Protein Length
313
NCBI Gene Symbol
SPDYA
NCBI GB Accession Number
SPDYA
Host or Source
Rabbit
Protein Name
Speedy protein A
Nucleotide Accession Number
NM_182756
Peptide Sequence
HTAGVTEKHSQDSYNSLSMDIIGDPSQAYTGSEVVNDHQSNKGKKTNFLK
Curated Selection
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