SPDYA Antibody - N-terminal region : HRP (ARP55845_P050-HRP)
Product Specifications
Gene Name
Speedy homolog A (Xenopus laevis)
Gene Aliases
SPY1, SPDY1, RINGO3, RINGOA
Gene ID
245711
Swiss Prot
Q5MJ70
Accession Number
NP_877433
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human SPDYA
Target
SPDYA regulates the G1/S phase transition of the cell cycle by binding and activating CDC2, CDK2 and CDKN1B/KIP1. SPDYA can activate CDK2 without promoting CDK2 phosphorylation. SPDYA mediates cell survival during the DNA damage process through activation of CDK2.
Partner Proteins
CDK2; UBC; SKP2; CDKN1B
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 92%; Dog: 100%; Human: 100%; Mouse: 85%; Pig: 100%; Rabbit: 85%; Rat: 100%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
36kDa
References & Citations
McAndrew, C.W., (2007) Cell Cycle 6 (15), 1937-1945
Shipping Conditions
Wet Ice
Protein Length
313
NCBI Gene Symbol
SPDYA
NCBI GB Accession Number
SPDYA
Host or Source
Rabbit
Protein Name
Speedy protein A
Nucleotide Accession Number
NM_182756
Peptide Sequence
MRHNQMCCETPPTVTVYVKSGSNRSHQPKKPITLKRPICKDNWQAFEKNT
Frequently Asked Questions
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