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PLCB1 Antibody - middle region : Biotin (ARP55844_P050-Biotin)

Product Specifications

Gene Name

Phospholipase C, beta 1 (phosphoinositide-specific)

Gene Aliases

DEE12, PLC-I, EIEE12, PI-PLC, PLC154, PLCB1A, PLCB1B, PLC-154, PLC-beta-1

Gene ID

23236

Swiss Prot

D3DW13

Accession Number

NP_877398

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PLCB1

Target

The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction

Partner Proteins

TFCP2; CTBP2; CTBP1; CEP76; PLCB1; GNAQ; SLC9A3R1; GNA11; PCF11; UBC; KRIT1; SPTBN1; TRPC3; TRPM7; PARD6A; PARD3; RGS4; RGS12; MAPK3; PRKCD; PRKCA; MAPK1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

There is BioGPS gene expression data showing that PLCB1 is expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

134kDa

References & Citations

Fantuzzi, L., (2008) Blood 111 (7), 3355-3363

Shipping Conditions

Wet Ice

Protein Length

1173

NCBI Gene Symbol

PLCB1

NCBI GB Accession Number

PLCB1

Host or Source

Rabbit

Protein Name

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1

Nucleotide Accession Number

NM_182734

Peptide Sequence

EAQSKRQEKLVEKHKEIRQQILDEKPKGEGSSSFLSETCHEDPSVSPNFT

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