USP12 Antibody - middle region : Biotin (ARP55812_P050-Biotin)
Product Specifications
Gene Name
Ubiquitin specific peptidase 12
Gene Aliases
UBH1, USP12L1
Gene ID
219333
Swiss Prot
O75317
Accession Number
NP_872294
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human USP12
Target
USP12 is a deubiquitinating enzyme. USP12 has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. USP12 is not involved in deubiquitination of monoubiquitinated FANCD2.
Partner Proteins
PHLPP1; PHLPP2; NOTCH1; AR; WDR48; UBC; APP; ITCH; WDR20; WDR26; WDR77; HIST2H2BE; HIST2H2AC; DMWD; RAD51AP1; PAIP1; MMP2; DHX8; USP46; UCHL5; SDF4; NUP160; USP39
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
43kDa
References & Citations
Dunham, A., (2004) Nature 428 (6982), 522-528
Shipping Conditions
Wet Ice
Protein Length
370
NCBI Gene Symbol
USP12
NCBI GB Accession Number
USP12
Host or Source
Rabbit
Protein Name
Ubiquitin carboxyl-terminal hydrolase 12
Nucleotide Accession Number
NM_182488
Peptide Sequence
ITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLPNG
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