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USP12 Antibody - middle region : Biotin (ARP55812_P050-Biotin)

Product Specifications

Gene Name

Ubiquitin specific peptidase 12

Gene Aliases

UBH1, USP12L1

Gene ID

219333

Swiss Prot

O75317

Accession Number

NP_872294

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human USP12

Target

USP12 is a deubiquitinating enzyme. USP12 has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. USP12 is not involved in deubiquitination of monoubiquitinated FANCD2.

Partner Proteins

PHLPP1; PHLPP2; NOTCH1; AR; WDR48; UBC; APP; ITCH; WDR20; WDR26; WDR77; HIST2H2BE; HIST2H2AC; DMWD; RAD51AP1; PAIP1; MMP2; DHX8; USP46; UCHL5; SDF4; NUP160; USP39

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

43kDa

References & Citations

Dunham, A., (2004) Nature 428 (6982), 522-528

Shipping Conditions

Wet Ice

Protein Length

370

NCBI Gene Symbol

USP12

NCBI GB Accession Number

USP12

Host or Source

Rabbit

Protein Name

Ubiquitin carboxyl-terminal hydrolase 12

Nucleotide Accession Number

NM_182488

Peptide Sequence

ITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLPNG

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