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FYN Antibody - N-terminal region : HRP (ARP55567_P050-HRP)

Selected Variant

ARP55567_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

FYN oncogene related to SRC, FGR, YES

Gene Aliases

SLK, SYN, p59-FYN

Gene ID

2534

Swiss Prot

P06241

Accession Number

NP_694593

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human FYN

Target

FYN is a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein.This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist.

Partner Proteins

IFITM3; EFS; WBP11; MAPT; IKBKG; PRMT6; KDM1A; SUV39H1; CMA1; TNF; IL1B; STAT3; HSP90AA1; GRIN2B; GRIN1; Mbp; MED28; CBL; TCAP; UBC; PDE4D; ENO1; SNCA; FYB; CLTC; LAT; SKAP2; ADAM15; nef; CD244; FYN; CAV1; VAV2; VAV1; ATXN1; PTPN11; KCNJ3; KCNA5; KCNA4; K

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

FYN is strongly supported by BioGPS gene expression data to be expressed in HEK293T

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

54kDa

References & Citations

Hoe, H.S., (2008) J. Biol. Chem. 283 (10), 6288-6299

Shipping Conditions

Wet Ice

Protein Length

482

NCBI Gene Symbol

FYN

NCBI GB Accession Number

FYN

Host or Source

Rabbit

Protein Name

Tyrosine-protein kinase Fyn

Nucleotide Accession Number

NM_153048

Peptide Sequence

GCVQCKDKEATKLTEERDGSLNQSSGYRYGTDPTPQHYPSFGVTSIPNYN

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