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SENP5 Antibody - middle region : Biotin (ARP55489_P050-Biotin)

Product Specifications

Gene Name

SUMO1/sentrin specific peptidase 5

Gene Aliases

DKFZp564O1016, FLJ42398, MGC27076

Gene ID

205564

Swiss Prot

Q96HI0

Accession Number

NP_689912

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SENP5

Target

The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates.

Partner Proteins

RABGAP1; SUMO3; PASK; SUMO2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

87kDa

References & Citations

Gong, L. (2006) J. Biol. Chem. 281 (23), 15869-15877

Shipping Conditions

Wet Ice

Protein Length

755

NCBI Gene Symbol

SENP5

NCBI GB Accession Number

SENP5

Host or Source

Rabbit

Protein Name

Sentrin-specific protease 5

Nucleotide Accession Number

NM_152699

Peptide Sequence

LSGFLDEVMKKYGSLVPLSEKEVLGRLKDVFNEDFSNRKPFINREITNYR

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