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GNAO1 Antibody - middle region: FITC (ARP55425_P050-FITC)

Product Specifications

Gene Name

Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O

Gene Aliases

GNAO, DEE17, NEDIM, EIEE17, HLA-DQB1, G-ALPHA-o

Gene ID

2775

Swiss Prot

B3KP89

Accession Number

NP_620073

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human GNAO1

Target

Activated Goalpha interacted directly with PLZF, and enhanced its function as a transcriptional and cell growth suppressor. Goalpha might play a role in mediating extracellular signal-regulated kinase activation by G protein-coupled receptors in the brain.

Partner Proteins

UBC; ADRA2A; BAG3; Htt; RGS9; GABBR1; Haus4; RGS1; RIC8A; DCTN2; KLHL3; SCN8A; PDE6G; CRHR1; GPSM2; HRH4; NGB; S1PR5; RGS19; GRM6; FFAR2; TSHR; RGS5; RGS10; RGS7; RGS4; RGS16; RGS14; PTPRU; CCR5; NUCB1; PDE6H; CACNA1B; OPRM1; OPRD1; GNAO1; GNAI1; ADRA2C

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

There is BioGPS gene expression data showing that GNAO1 is expressed in 721_B

Concentration

0.5 mg/mL

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Yeast: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

40kDa

Shipping Conditions

Wet Ice

Protein Length

354

NCBI Gene Symbol

GNAO1

Protein Name

CDNA FLJ31446 fis, clone NT2NE2000909, highly similar to Guanine nucleotide-binding protein G (o) subunit alpha 1 EMBL BAG51601.1

Nucleotide Accession Number

NM_138736

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