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GNAO1 Antibody - N-terminal region : Biotin (ARP55424_P050-Biotin)

Selected Variant

ARP55424_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O

Gene Aliases

GNAO, DEE17, NEDIM, EIEE17, HLA-DQB1, G-ALPHA-o

Gene ID

2775

Swiss Prot

P09471

Accession Number

NP_620073

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human GNAO1

Target

Activated Goalpha interacted directly with PLZF, and enhanced its function as a transcriptional and cell growth suppressor. Goalpha might play a role in mediating extracellular signal-regulated kinase activation by G protein-coupled receptors in the brain

Partner Proteins

UBC; ADRA2A; BAG3; Htt; RGS9; GABBR1; Haus4; RGS1; RIC8A; DCTN2; KLHL3; SCN8A; PDE6G; CRHR1; GPSM2; HRH4; NGB; S1PR5; RGS19; GRM6; FFAR2; TSHR; RGS5; RGS10; RGS7; RGS4; RGS16; RGS14; PTPRU; CCR5; NUCB1; PDE6H; CACNA1B; OPRM1; OPRD1; GNAO1; GNAI1; ADRA2C

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 79%; Rabbit: 100%; Rat: 93%; Sheep: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

40kDa

References & Citations

Won, J.H., (2008) Cell. Signal. 20 (5), 884-891

Shipping Conditions

Wet Ice

Protein Length

354

NCBI Gene Symbol

GNAO1

NCBI GB Accession Number

GNAO1

Host or Source

Rabbit

Protein Name

Guanine nucleotide-binding protein G (o) subunit alpha

Nucleotide Accession Number

NM_138736

Peptide Sequence

PVVYSNTIQSLAAIVRAMDTLGIEYGDKERKADAKMVCDVVSRMEDTEPF

Subunit

Alpha

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