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KRAS Antibody - N-terminal region : FITC (ARP55408_P050-FITC)

Product Specifications

Gene Name

V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog

Gene Aliases

NS, NS3, OES, CFC2, RALD, K-Ras, KRAS1, KRAS2, RASK2, KI-RAS, C-K-RAS, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, K-Ras 2, 'C-K-RAS, c-Ki-ras, c-Ki-ras2

Gene ID

3845

Swiss Prot

P01111

Accession Number

NP_203524

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human KRAS

Target

KRAS is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma.

Partner Proteins

RBPMS; UBC; PSMA3; ARAF; MDFI; TRAF6; BCL2; BTRC; RAF1; MAPK1; PHB; DDX50; EGLN1; DDX47; RALGDS; RGL2; PIK3R2; LPAR1; ADH6; APP; ELAVL1; CALM1; IGSF21; CCT7; PDE4DIP; DNAJA3; EEF1A1; RASGRF2; RASSF2; RAP1GDS1; RASGRP2; RASSF5; SHOC2; PGGT1B; PIK3CG; EPB42

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

22kDa

Shipping Conditions

Wet Ice

Product Datasheet

Anti-KRAS (ARP55408_P050-FITC) antibody

Specificity

100% homologous to human KRAS, NRAS and HRAS.

Protein Length

189

NCBI Gene Symbol

KRAS

NCBI GB Accession Number

KRAS

Host or Source

Rabbit

Protein Name

GTPase NRas

Nucleotide Accession Number

NM_033360

Peptide Sequence

TEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETC

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