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FANCE Antibody - middle region : Biotin (ARP55381_P050-Biotin)

Product Specifications

Gene Name

Fanconi anemia, complementation group E

Gene Aliases

FAE, FACE

Gene ID

2178

Swiss Prot

Q9HB96

Accession Number

NP_068741

Host

Rabbit

Reactivity

Human, Cow, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human FANCE

Target

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2) . The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex.The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2) . The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group E. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

APITD1; STRA13; UBC; FANCG; FANCD2; FANCC; FANCA; FANCM; C1orf86; ELAVL1; Erh; FANCF; CHEK1; HES1; PCNA; BRCA2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 79%; Horse: 85%; Human: 100%; Pig: 79%; Rabbit: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

59kDa

References & Citations

Wang, X., (2007) Mol. Cell. Biol. 27 (8), 3098-3108

Shipping Conditions

Wet Ice

Protein Length

536

NCBI Gene Symbol

FANCE

NCBI GB Accession Number

FANCE

Host or Source

Rabbit

Protein Name

Fanconi anemia group E protein

Nucleotide Accession Number

NM_021922

Peptide Sequence

SPQAPDPEEEENRDSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDH

Frequently Asked Questions

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