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GSPT2 Antibody - N-terminal region : HRP (ARP55356_P050-HRP)

Selected Variant

ARP55356_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

G1 to S phase transition 2

Gene Aliases

GST2, ERF3B

Gene ID

23708

Swiss Prot

Q8IYD1

Accession Number

NP_060564

Host

Rabbit

Reactivity

Human, Mouse, Rat, Horse, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human GSPT2

Target

GSPT2 is closely related to GSPT1, a GTP-binding protein that plays an essential role at the G1- to S-phase transition of the cell cycle in yeast and human cells. GSPT1 is a positive regulator of translational accuracy and, in a binary complex with eRF1, functions as a polypeptide chain release factor.GSPT2 is closely related to GSPT1 (MIM 139259), a GTP-binding protein that plays an essential role at the G1- to S-phase transition of the cell cycle in yeast and human cells. GSPT1 is a positive regulator of translational accuracy and, in a binary complex with eRF1 (MIM 600285), functions as a polypeptide chain release factor.[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-207 BC036077.1 1-207 208-1527 AJ251548.1 12-1331 1528-2497 AK001303.1 1512-2481 2498-2503 AK023155.1 2487-2492

Partner Proteins

UBC; ATG7; STAT1; SNX2; SNX1; SHMT2; SHMT1; RDX; NASP; IDE; GSPT1; CTTN; ATP6V1C1; UPF1; PABPC1; SMG1; CCT2; APP; UBR5; ETF1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Horse: 86%; Human: 100%; Mouse: 86%; Pig: 86%; Rat: 86%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

69kDa

References & Citations

Chauvin, C., (2005) Mol. Cell. Biol. 25 (14), 5801-5811

Shipping Conditions

Wet Ice

Protein Length

628

NCBI Gene Symbol

GSPT2

NCBI GB Accession Number

GSPT2

Host or Source

Rabbit

Protein Name

Eukaryotic peptide chain release factor GTP-binding subunit ERF3B

Nucleotide Accession Number

NM_018094

Peptide Sequence

MALEESWEHSKEVSEAEPGGGSSGDSGPPEESGQEMMEEKEEIRKSKSVI

Subunit

ERF3B

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