SENP3 Antibody - N-terminal region : Biotin (ARP55322_P050-Biotin)
Product Specifications
Gene Name
SUMO1/sentrin/SMT3 specific peptidase 3
Gene Aliases
SSP3, Ulp1, SMT3IP1
Gene ID
26168
Swiss Prot
Q9H4L4
Accession Number
NP_056485
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human SENP3
Target
SENP3 is a protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates. SENP3 deconjugates SUMO2 from MEF2D, which increases its transcriptional activation capability.
Partner Proteins
HIF1A; EP300; UBC; SUMO2; WDR5; ASH2L; KMT2D; RBBP5; KMT2A; MEN1; RNF2; HECW2; SOX2; LAS1L; PELP1; CDK6; CDK4; MOV10; CHCHD4; DHX15; ILF3; TRIM63; TRIM54; USP21; USP15; CDKN2A; RPS18; RPS11; RPS8; RPS4X; RPLP0; NPM1; PIDD1; NR1H2; TP53; MDM2; STUB1; HSP90
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IF, WB
Purification
Affinity Purified
Sample Type
SENP3 is strongly supported by BioGPS gene expression data to be expressed in 721_B. HeLa
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
65kDa
References & Citations
Haindl, M., (2008) EMBO Rep. 9 (3), 273-279
Shipping Conditions
Wet Ice
Protein Length
574
NCBI Gene Symbol
SENP3
NCBI GB Accession Number
SENP3
Host or Source
Rabbit
Protein Name
Sentrin-specific protease 3
Nucleotide Accession Number
NM_015670
Peptide Sequence
PPPKPRLKSGGGFGPDPGSGTTVPARRLPVPRPSFDASASEEEEEEEEEE
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