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SH2B1 Antibody - middle region : Biotin (ARP55271_P050-Biotin)

Product Specifications

Gene Name

SH2B adaptor protein 1

Gene Aliases

PSM, SH2B

Gene ID

25970

Swiss Prot

Q9NRF2-2

Accession Number

NP_056318

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SH2B1

Target

SH2B1 is a member of the SH2-domain containing mediators family. SH2B1 mediates activation of various kinases and may function in cytokine and growth factor receptor signaling and cellular transformation.

Partner Proteins

FGFR3; SH2B1; SH2B2; JAK2; INSR; IGF1R; RHBG; EGFR; IRS1; BRCA1; KIAA0319; NTRK2; NTRK1; GRB2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

71kDa

References & Citations

Donatello, S., (2007) Oncogene 26 (45), 6546-6559

Shipping Conditions

Wet Ice

Protein Length

671

NCBI Gene Symbol

SH2B1

NCBI GB Accession Number

SH2B1

Host or Source

Rabbit

Protein Name

SH2B adapter protein 1

Nucleotide Accession Number

NM_015503

Peptide Sequence

GTSFLTRENTDSLELSCLNHSESLPSQDLLLGPSESNDRLSQGAYGGLSD

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