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HISPPD1 Antibody - middle region : Biotin (ARP55203_P050-Biotin)

Product Specifications

Gene Name

Diphosphoinositol pentakisphosphate kinase 2

Gene Aliases

VIP2, IP7K2, CFAP160, DFNB100, HISPPD1

Gene ID

23262

Swiss Prot

O43314

Accession Number

NP_056031

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human HISPPD1

Target

Inositol phosphates (IPs) and diphosphoinositol phosphates (PP-IPs), also known as inositol pyrophosphates, act as cell signaling molecules. HISPPD1 has both IP6 kinase (EC 2.7.4.21) and PP-IP5 (also called IP7) kinase (EC 2.7.4.24) activities that produce the high-energy pyrophosphates PP-IP5 and PP2-IP4 (also called IP8), respectively.Inositol phosphates (IPs) and diphosphoinositol phosphates (PP-IPs), also known as inositol pyrophosphates, act as cell signaling molecules. HISPPD1 has both IP6 kinase (EC 2.7.4.21) and PP-IP5 (also called IP7) kinase (EC 2.7.4.24) activities that produce the high-energy pyrophosphates PP-IP5 and PP2-IP4 (also called IP8), respectively (Fridy et al., 2007 [PubMed 17690096]) .[supplied by OMIM].

Partner Proteins

UBC; ZBTB8B; THOC7; ZC3H15; VAC14; WDR74; WDR6; SUMO1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

138kDa

References & Citations

Choi, J.H., (2007) J. Biol. Chem. 282 (42), 30763-30775

Shipping Conditions

Wet Ice

Protein Length

1222

NCBI Gene Symbol

PPIP5K2

NCBI GB Accession Number

PPIP5K2

Host or Source

Rabbit

Protein Name

Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2

Nucleotide Accession Number

NM_015216

Peptide Sequence

SLSSCQQRVKARLHEILQKDRDFTAEDYEKLTPSGSISLIKSMHLIKNPV

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