FTSJD2 Antibody - C-terminal region: HRP (ARP55152_P050-HRP)
Product Specifications
Gene Name
FtsJ methyltransferase domain containing 2
Gene Aliases
MTr1, hMTr1, FTSJD2, KIAA0082
Gene ID
23070
Swiss Prot
Q8N1G2
Accession Number
NP_055865
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human FTSJD2
Target
FTSJD2 is a S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. It methylates the ribose of the first nucleotide of a m7GpppG-capped mRNA to produce m7GpppNmp (cap1) . Cap1 modification is linked to higher levels of translation. It may be involved in the interferon response pathway.
Partner Proteins
UBC; CUL3
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 86%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
95kDa
Shipping Conditions
Wet Ice
Protein Length
835
NCBI Gene Symbol
CMTR1
Protein Name
Cap-specific mRNA (nucleoside-2'-O-) -methyltransferase 1
Nucleotide Accession Number
NM_015050
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