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FTSJD2 Antibody - C-terminal region : HRP (ARP55152_P050-HRP)

Product Specifications

Gene Name

FtsJ methyltransferase domain containing 2

Gene Aliases

MTr1, hMTr1, FTSJD2, KIAA0082

Gene ID

23070

Swiss Prot

Q8N1G2

Accession Number

NP_055865

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human FTSJD2

Target

FTSJD2 is a S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. It methylates the ribose of the first nucleotide of a m7GpppG-capped mRNA to produce m7GpppNmp (cap1) . Cap1 modification is linked to higher levels of translation. It may be involved in the interferon response pathway.

Partner Proteins

UBC; CUL3

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

95kDa

Shipping Conditions

Wet Ice

Protein Length

835

NCBI Gene Symbol

CMTR1

NCBI GB Accession Number

CMTR1

Host or Source

Rabbit

Protein Name

Cap-specific mRNA (nucleoside-2'-O-) -methyltransferase 1

Nucleotide Accession Number

NM_015050

Peptide Sequence

YRLEEMEKIFVRLEMKIIKGSSGTPKLSYTGRDDRHFVPMGLYIVRTVNE

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