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KIFAP3 Antibody - middle region : Biotin (ARP55128_P050-Biotin)

Selected Variant

ARP55128_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Kinesin-associated protein 3

Gene Aliases

FLA3, KAP3, SMAP, KAP-1, KAP-3, Smg-GDS, dJ190I16.1

Gene ID

22920

Swiss Prot

Q92845

Accession Number

NP_055785

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human KIFAP3

Target

The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein.

Partner Proteins

NAA10; NCF2; UBC; PEX19; RBFOX1; KIF3A; VHL; RANBP2; MEST; DISC1; NIPSNAP3A; NUDT21; AR; RAP1GDS1; MINK1; SMC3; KIF3B; KIFAP3; MAP3K10; RPGR; SRC; APC; MAP3K11

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

91kDa

Shipping Conditions

Wet Ice

Protein Length

792

NCBI Gene Symbol

KIFAP3

NCBI GB Accession Number

KIFAP3

Host or Source

Rabbit

Protein Name

Kinesin-associated protein 3

Nucleotide Accession Number

NM_014970

Peptide Sequence

WLEMVESRQMDESEQYLYGDDRIEPYIHEGDILERPDLFYNSDGLIASEG

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