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PPP6R1 Antibody - N-terminal region : Biotin (ARP55109_P050-Biotin)

Selected Variant

ARP55109_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Protein phosphatase 6, regulatory subunit 1

Gene Aliases

PP6R1, SAPS1, SAP190, KIAA1115

Gene ID

22870

Swiss Prot

Q9UPN7

Accession Number

NP_055746

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PPP6R1

Target

Protein phosphatase regulatory subunits, such as SAPS1, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS1 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 300141) (Stefansson and Brautigan, 2006 [PubMed 16769727]) .

Partner Proteins

UBC; AGO1; ANKRD52; MOB1B; ANKRD44; ACAD11; SRPRB; PPP6R3; MOB1A; CNOT10; ANKRD28; CNOT1; ILVBL; PFDN6; C2CD5; KNTC1; PPP6R2; GTF3C4; ARHGEF2; USP10; SGPL1; IKBKAP; TTF2; SRPR; PPP6C; PFDN5; PFDN2; PDCD2; HSPA4; HADHB; HADHA; ACSL3; ALDH3A2; EGFR; HDAC11

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

PPP6R1 is supported by BioGPS gene expression data to be expressed in RPMI 8226

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

97kDa

Shipping Conditions

Wet Ice

Protein Length

881

NCBI Gene Symbol

PPP6R1

NCBI GB Accession Number

PPP6R1

Host or Source

Rabbit

Protein Name

Serine/threonine-protein phosphatase 6 regulatory subunit 1

Nucleotide Accession Number

NM_014931

Peptide Sequence

MFWKFDLHTSSHLDTLLEREDLSLPELLDEEDVLQECKVVNRKLLDFLLQ

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