PPP6R1 Antibody - N-terminal region : Biotin (ARP55109_P050-Biotin)
Product Specifications
Gene Name
Protein phosphatase 6, regulatory subunit 1
Gene Aliases
PP6R1, SAPS1, SAP190, KIAA1115
Gene ID
22870
Swiss Prot
Q9UPN7
Accession Number
NP_055746
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human PPP6R1
Target
Protein phosphatase regulatory subunits, such as SAPS1, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS1 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 300141) (Stefansson and Brautigan, 2006 [PubMed 16769727]) .
Partner Proteins
UBC; AGO1; ANKRD52; MOB1B; ANKRD44; ACAD11; SRPRB; PPP6R3; MOB1A; CNOT10; ANKRD28; CNOT1; ILVBL; PFDN6; C2CD5; KNTC1; PPP6R2; GTF3C4; ARHGEF2; USP10; SGPL1; IKBKAP; TTF2; SRPR; PPP6C; PFDN5; PFDN2; PDCD2; HSPA4; HADHB; HADHA; ACSL3; ALDH3A2; EGFR; HDAC11
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
PPP6R1 is supported by BioGPS gene expression data to be expressed in RPMI 8226
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
97kDa
Shipping Conditions
Wet Ice
Protein Length
881
NCBI Gene Symbol
PPP6R1
NCBI GB Accession Number
PPP6R1
Host or Source
Rabbit
Protein Name
Serine/threonine-protein phosphatase 6 regulatory subunit 1
Nucleotide Accession Number
NM_014931
Peptide Sequence
MFWKFDLHTSSHLDTLLEREDLSLPELLDEEDVLQECKVVNRKLLDFLLQ
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