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FAM120A Antibody - middle region : Biotin (ARP55089_P050-Biotin)

Selected Variant

ARP55089_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Family with sequence similarity 120A

Gene Aliases

OSSA, C9orf10, HBVPTPAP

Gene ID

23196

Swiss Prot

Q9NZB2

Accession Number

NP_055427

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human FAM120A

Target

FAM120A may participate in mRNA transport in the cytoplasm. FAM120A is the critical component of the oxidative stress-induced survival signaling. It activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. FAM120A binds RNA and promotes the secretion of IGF-II. It may play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses.

Partner Proteins

SPRTN; CEP250; SUMO2; STAU1; UBC; PASK; SUMO1; NEDD8; RNF2; EZH2; BMI1; HECW2; TARDBP; CFTR; GRK5; CAND1; CUL3; SIRT7; Ybx1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

FAM120A is strongly supported by BioGPS gene expression data to be expressed in HeLa, MCF7

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 85%; Pig: 100%; Rabbit: 92%; Rat: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

122kDa

References & Citations

Olsen, J.V., (2006) Cell 127 (3), 635-648

Shipping Conditions

Wet Ice

Protein Length

1118

NCBI Gene Symbol

FAM120A

NCBI GB Accession Number

FAM120A

Host or Source

Rabbit

Protein Name

Constitutive coactivator of PPAR-gamma-like protein 1

Nucleotide Accession Number

NM_014612

Peptide Sequence

SGGATNHISGNKIGWEKTGSHSEPQARGDPGDQTKAEGSSTASSGSQLAE

Price

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