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SENP1 Antibody - middle region : Biotin (ARP55082_P050-Biotin)

Product Specifications

Gene Name

SUMO1/sentrin specific peptidase 1

Gene Aliases

SuPr-2

Gene ID

29843

Swiss Prot

Q9P0U3-2

Accession Number

NP_055369

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SENP1

Target

The covalent modification of proteins by the small ubiquitin-like protein SUMO is implicated in the regulation of nucleocytoplasmic transport, genomic stability, gene transcription, and other processes. Sumoylation is catalyzed on target lysine residues by a multienzyme process and is reversed by desumoylating enzymes such as SENP1.

Partner Proteins

USP25; RABGAP1; SUMO1; TP53; SP100; SUMO2; SUMO3; RANGAP1; PRDM1; BAG3; LMNA; APP; UBD; U90; HIPK2; ISG15; RANBP2; HDAC2; ELAVL1; UBC; GCM1; RUVBL2; HDAC1; PARP1; HDAC4; KCNK1; SENP1; SP3

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 77%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

73kDa

References & Citations

Ohbayashi, N., (2008) Biochem. Biophys. Res. Commun. 371 (4), 823-828

Shipping Conditions

Wet Ice

Protein Length

643

NCBI Gene Symbol

SENP1

NCBI GB Accession Number

SENP1

Host or Source

Rabbit

Protein Name

Sentrin-specific protease 1

Nucleotide Accession Number

NM_014554

Peptide Sequence

PQQMNGSDCGMFACKYADCITKDRPINFTQQHMPYFRKRMVWEILHRKLL

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