SENP1 Antibody - middle region : Biotin (ARP55082_P050-Biotin)
Product Specifications
Gene Name
SUMO1/sentrin specific peptidase 1
Gene Aliases
SuPr-2
Gene ID
29843
Swiss Prot
Q9P0U3-2
Accession Number
NP_055369
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human SENP1
Target
The covalent modification of proteins by the small ubiquitin-like protein SUMO is implicated in the regulation of nucleocytoplasmic transport, genomic stability, gene transcription, and other processes. Sumoylation is catalyzed on target lysine residues by a multienzyme process and is reversed by desumoylating enzymes such as SENP1.
Partner Proteins
USP25; RABGAP1; SUMO1; TP53; SP100; SUMO2; SUMO3; RANGAP1; PRDM1; BAG3; LMNA; APP; UBD; U90; HIPK2; ISG15; RANBP2; HDAC2; ELAVL1; UBC; GCM1; RUVBL2; HDAC1; PARP1; HDAC4; KCNK1; SENP1; SP3
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 77%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
73kDa
References & Citations
Ohbayashi, N., (2008) Biochem. Biophys. Res. Commun. 371 (4), 823-828
Shipping Conditions
Wet Ice
Protein Length
643
NCBI Gene Symbol
SENP1
NCBI GB Accession Number
SENP1
Host or Source
Rabbit
Protein Name
Sentrin-specific protease 1
Nucleotide Accession Number
NM_014554
Peptide Sequence
PQQMNGSDCGMFACKYADCITKDRPINFTQQHMPYFRKRMVWEILHRKLL
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