TMOD3 Antibody - N-terminal region : Biotin (ARP55077_P050-Biotin)
Product Specifications
Gene Name
Tropomodulin 3 (ubiquitous)
Gene Aliases
UTMOD
Gene ID
29766
Swiss Prot
Q9NYL9
Accession Number
NP_055362
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human TMOD3
Target
TMOD3 belongs to the tropomodulin family. It blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. This gene is a necessary element in receptor tyrosine kinase pathways, possibly as a tyrosine phosphorylation target. It is involved in regulation of RAF in the MAPK pathway and may also play a role in a MAPK-independent pathway.
Partner Proteins
UBC; PABPC1; YWHAE; PSMD9; PPP1CA; DHX15; PAN2; CSNK2A1; HNRNPUL2; PPIL3; AHCYL1; SULT1A1; PSMC4; PSMB7; NPC1; ATP6V1B1; LRRK2; FBXO25; ISG15; ARRB2; ARRB1; ELAVL1; SUMO2; DUSP23; TNFSF11; MAP1LC3B; Poc1b; Tubgcp3; Sass6; Trim69; Stag2; Pafah1b1; Erh; Cdk
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
39kDa
References & Citations
Weber, K.L., J. Cell. Sci. 120 (PT 20), 3625-3632 (2007)
Shipping Conditions
Wet Ice
Protein Length
352
NCBI Gene Symbol
TMOD3
NCBI GB Accession Number
TMOD3
Host or Source
Rabbit
Protein Name
Tropomodulin-3
Nucleotide Accession Number
NM_014547
Peptide Sequence
LDDLDPENALLPAGFRQKNQTSKSTTGPFDREHLLSYLEKEALEHKDRED
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