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RABGEF1 Antibody - N-terminal region : Biotin (ARP55073_P050-Biotin)

Selected Variant

ARP55073_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

RAB guanine nucleotide exchange factor (GEF) 1

Gene Aliases

RAP1, RABEX5, rabex-5

Gene ID

27342

Swiss Prot

A8K3R3

Accession Number

NP_055319

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human RABGEF1

Target

RABGEF1 forms a complex with rabaptin-5 (RABPT5; MIM 603616) that is required for endocytic membrane fusion, and it serves as a specific guanine nucleotide exchange factor (GEF) for RAB5 (RAB5A; MIM 179512) (Horiuchi et al., 1997 [PubMed 9323142]) .

Partner Proteins

TRIM15; CIPC; ZC2HC1C; TRIM54; RABGEF1; BLOC1S6; TXN2; THOC1; DAZAP2; UBC; TEAD4; RABEP1; DGCR6; TNKS1BP1; ROCK2; SLMAP; MON1A; RNF11; MON1B; RAB21; UBE2D3; UBE2D1; RAB5A; L1CAM; EEA1; ESR1; EGFR; RAB22A; GGA1; MAPK1; HRAS; YWHAG; YWHAB; KXD1; GGA2; RNF16

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

RABGEF1 is supported by BioGPS gene expression data to be expressed in HT1080

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

57kDa

Shipping Conditions

Wet Ice

Protein Length

491

NCBI Gene Symbol

RABGEF1

NCBI GB Accession Number

RABGEF1

Host or Source

Rabbit

Protein Name

CDNA FLJ75284, highly similar to Homo sapiens RAB guanine nucleotide exchange factor (GEF) 1 (RABGEF1), mRNA EMBL BAF83367.1

Nucleotide Accession Number

NM_014504

Peptide Sequence

MSLKSERRGIHVDQSDLLCKKGCGYYGNPAWQGFCSKCWREEYHKARQKQ

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