EDC4 Antibody - N-terminal region : Biotin (ARP55023_P050-Biotin)
Product Specifications
Gene Name
Enhancer of mRNA decapping 4
Gene Aliases
GE1, Ge-1, RCD8, HEDL5, HEDLS, RCD-8
Gene ID
23644
Swiss Prot
Q6P2E9
Accession Number
NP_055144
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human EDC4
Target
In the process of mRNA degradation, EDC4 seems to play a role in mRNA decapping. It is the component of a complex containing DCP2 and DCP1A which functions in decapping of ARE-containing mRNAs. EDC4 promotes complex formation between DCP1A and DCP2.It enhances the catalytic activity of DCP2 (in vitro) .
Partner Proteins
MDM2; DCP1B; DCP1A; UBC; DCP2; LGR4; WWOX; RPA3; RPA2; RPA1; BMI1; DIMT1; NELFB; IGF2BP3; G3BP1; EIF2B2; EIF2B3; RFC4; NMT1; ILF2; FKBP3; DDX1; ABCF1; ZFP36; YTHDC1; EDC3; vpu; GIT2; FBLN1; CCL5; UPF1; CRK; SIRT7; EIF2AK2; Edc4; Pds5a; tat
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
152kDa
References & Citations
Li, J.J. (2005) Mol. Cell 20 (6), 905-915
Shipping Conditions
Wet Ice
Protein Length
1401
NCBI Gene Symbol
EDC4
NCBI GB Accession Number
EDC4
Host or Source
Rabbit
Protein Name
Enhancer of mRNA-decapping protein 4
Nucleotide Accession Number
NM_014329
Peptide Sequence
LQEKQVICLSGDDSSTCIGILAKEVEIVASSDSSISSKARGSNKVKIQPV
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