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PIK3R5 Antibody - N-terminal region : Biotin (ARP55011_P050-Biotin)

Selected Variant

ARP55011_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Phosphoinositide-3-kinase, regulatory subunit 5

Gene Aliases

P101, FOAP-2, P101-PI3K, F730038I15Rik

Gene ID

23533

Swiss Prot

Q8WYR1

Accession Number

NP_055123

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PIK3R5

Target

Receptor-regulated class I phosphoinositide 3-kinases (PI3Ks) phosphorylate the membrane lipid phosphatidylinositol 4,5-bisphosphate (PtdIns (4,5) P2) to PtdIns (3,4,5) P3, which in turn recruits and activates cytosolic effectors involved in proliferation, survival, or chemotaxis. PIK3R5 is a PI3K regulatory subunit.Receptor-regulated class I phosphoinositide 3-kinases (PI3Ks) phosphorylate the membrane lipid phosphatidylinositol 4,5-bisphosphate (PtdIns (4,5) P2) to PtdIns (3,4,5) P3, which in turn recruits and activates cytosolic effectors involved in proliferation, survival, or chemotaxis. PIK3R5 is a PI3K regulatory subunit (Brock et al., 2003 [PubMed 12507995]) .[supplied by OMIM]. Sequence Note: removed 2 bases from the 3' end that did not align to the reference genome assembly. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-3253 AF128881.1 1-3253

Partner Proteins

APP; UBC; SDHB; PIK3CG

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

97kDa

References & Citations

Johnson, C., (2007) Oncogene 26 (49), 7049-7057

Shipping Conditions

Wet Ice

Protein Length

880

NCBI Gene Symbol

PIK3R5

NCBI GB Accession Number

PIK3R5

Host or Source

Rabbit

Protein Name

Phosphoinositide 3-kinase regulatory subunit 5

Nucleotide Accession Number

NM_014308

Peptide Sequence

HRFLTWPVPYCSICQELLTFIDAELKAPGISYQRLVRAEQGLPIRSHRSS

Subunit

5

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