ITGB3BP Antibody - N-terminal region : Biotin (ARP55000_P050-Biotin)

This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.

PIH1D2; UBR7; ARFIP2; COL4A3BP; KIFC3; KDM1A; UBC; APP; CENPP; CENPO; SVIL; MAPK6; ACTN2; MTA1; ITGB3BP; DDX24; RECQL5; RXRA; ITGB3; NFKB1; ITGB5; ESR1; CCNA2; THRA; RELA; RXRG

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.