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PNMA3 Antibody - N-terminal region : HRP (ARP54945_P050-HRP)

Selected Variant

ARP54945_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Paraneoplastic Ma antigen 3

Gene Aliases

MA3, MA5

Gene ID

29944

Swiss Prot

Q9UL41

Accession Number

NP_037496

Host

Rabbit

Reactivity

Human, Rat, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PNMA3

Target

The specific function of the protein remains unknown.This gene is a member of the paraneoplastic antigen MA (PNMA) gene family, whose protein products share homology with retroviral Gag proteins. They are highly expressed in the brain and also in a range of tumors associated with serious neurological phenotypes. PMID:16407312 reports the presence of a functional -1 ribosomal frameshift signal (consisting of a heptanucleotide shift motif followed 3' by a pseudoknot structure) in this gene, however, the frame-shifted product has not been characterized.

Partner Proteins

PARD6G

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Horse: 93%; Human: 100%; Rat: 79%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

52kDa

References & Citations

Wills, N.M., (2006) J. Biol. Chem. 281 (11), 7082-7088

Shipping Conditions

Wet Ice

Protein Length

463

NCBI Gene Symbol

PNMA3

NCBI GB Accession Number

PNMA3

Host or Source

Rabbit

Protein Name

Paraneoplastic antigen Ma3

Nucleotide Accession Number

NM_013364

Peptide Sequence

QDIDYALLPREIPGKGGPWEVIVKPRNSDGEFLNRLNRFLEEERRTVSDM

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