POLL Antibody - middle region : HRP (ARP54924_P050-HRP)
Product Specifications
Gene Name
Polymerase (DNA directed), lambda
Gene Aliases
BETAN, POLKAPPA
Gene ID
27343
Swiss Prot
Q9UGP5
Accession Number
NP_037406
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Yeast
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human POLL
Target
POLL is a repair polymerase.It is involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
Partner Proteins
KRTAP10-3; KRTAP10-7; FAM9B; KRT40; FSD2; SSX2IP; TFIP11; PNMA1; TFCP2; MAGEA12; TRIM23; APP; DCUN1D1; REV1; LDOC1; RPA1; PCNA; CDK2; UBE2H; UBE2E1; UBE2D3; UBE2D2; UBE2D1
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 93%; Yeast: 83%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
63kDa
References & Citations
Picher, A.J. (2007) DNA Repair (Amst.) 6 (12), 1749-1756
Shipping Conditions
Wet Ice
Protein Length
575
NCBI Gene Symbol
POLL
NCBI GB Accession Number
POLL
Host or Source
Rabbit
Protein Name
DNA polymerase lambda
Nucleotide Accession Number
NM_013274
Peptide Sequence
SLSEHALSTAVVRNTHGCKVGPGRVLPTPTEKDVFRLLGLPYREPAERDW
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