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TBK1 Antibody - middle region : HRP (ARP54922_P050-HRP)

Selected Variant

ARP54922_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

TANK-binding kinase 1

Gene Aliases

NAK, T2K, IIAE8, FTDALS4

Gene ID

29110

Swiss Prot

Q9UHD2

Accession Number

NP_037386

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human TBK1

Target

The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitinat

Partner Proteins

UBC; Trim11; AZI2; TBK1; TANK; TBKBP1; EGFR; TMEM173; TRAF3; EXOC2; MIB1; LATS2; ANKRD28; DDX58; SYK; TRAF3IP2; TOMM70A; STX11; PROS1; IRF3; HSP90AA1; XIAP; RNF11; YWHAE; APP; NFKBIA; IKBKG; TRAF2; MAVS; OPTN; SRC; RELA; TICAM1; MBP; IRF7; IKBKE; HERC2; T

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

84kDa

References & Citations

Morton, S., (2008) FEBS Lett. 582 (6), 997-1002

Shipping Conditions

Wet Ice

Protein Length

729

NCBI Gene Symbol

TBK1

NCBI GB Accession Number

TBK1

Host or Source

Rabbit

Protein Name

Serine/threonine-protein kinase TBK1

Nucleotide Accession Number

NM_013254

Peptide Sequence

QEGTHPKDRNVEKLQVLLNCMTEIYYQFKKDKAERRLAYNEEQIHKFDKQ

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