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PTPN22 Antibody - middle region : Biotin (ARP54896_P050-Biotin)

Selected Variant

ARP54896_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Protein tyrosine phosphatase, non-receptor type 22

Gene Aliases

LYP, PEP, LYP1, LYP2, PTPN8, PTPN22.5, PTPN22.6

Gene ID

26191

Swiss Prot

Q9Y2R2

Accession Number

NP_001180360.1

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PTPN22

Target

This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Dog: 86%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 79%; Rat: 93%; Yeast: 82%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

61kDa

Shipping Conditions

Wet Ice

Protein Length

563

NCBI Gene Symbol

PTPN22

NCBI GB Accession Number

PTPN22

Host or Source

Rabbit

Protein Name

Tyrosine-protein phosphatase non-receptor type 22

Nucleotide Accession Number

NM_001193431.2

Peptide Sequence

TAPRIDDEIPPPLPVWTPESFIVVEEAGEFSPNVPKSLSSAVKVKIGTSL

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